Cold Plasma Explained and How It Differs from Conventional Air Purification A plain-language guide to Cold Plasma (DBD) — from the basic science to how it compares with HEPA filters, UV-C, ozone and chemical sprays — in one article. What Is Cold Plasma — and How Is It Different from HEPA Filters, UV, Ozone, and Chemical Sprays? Short answer — for readers who want it now What is Cold Plasma? Cold Plasma is the fourth state of matter — after solid, liquid and gas. High voltage ionizes air molecules, producing reactive species such as superoxide, hydroxyl radicals and singlet oxygen